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Correction of thrombocytopenia with small dose aspirin in the primary antiphospholipid syndrome
D Alarcón-Segovia1, J Sánchez-Guerrero
1Department of Immunology and Rheumatology, Instituto Nacional de la Nutrición Salvador Zubirán, Mexico City, Mexico.
The Journal of Rheumatology
|October 1, 1989
Abstract:
We describe 2 patients with primary antiphospholipid syndrome in whom thrombocytopenia, which had not responded to high dose prednisone treatment, was promptly corrected after they started taking small doses (100 mg/day) of aspirin. This effect has been sustained despite subsequent prednisone withdrawal. Theoretical reasons for such an apparent therapeutic effect of aspirin in these patients are discussed.