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Crystallization and preliminary X-ray investigation of a complex between a Fab fragment and its antigen, cyclosporin
D Altschuh1, H P Kocher, V F Quesniaux
1Laboratoire d'Immunochimie, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France.
Journal of Molecular Biology
|September 5, 1989
Abstract:
Preliminary crystallographic data are given for a complex between the cyclic undecapeptide cyclosporin and the Fab fragment of an anti-cyclosporin monoclonal antibody. Crystals of the complex are orthorhombic with space group P2(1)2(1)2(1) and diffract to 2.7 A resolution. The unit cell dimensions are a = 52.6 A, b = 70.2 A and c = 118.4 A. A native data set to 2.7 A resolution has been collected.