Related Experiment Video
Updated: Mar 8, 2026

Antibiotic Dereplication Using the Antibiotic Resistance Platform
Published on: October 17, 2019
Why new antibiotics are not obviously useful now
Grégory Dubourg1, Cédric Abat2, Didier Raoult1
1URMITE, UMR CNRS 6236-IRD 198, Faculté de Médecine, Aix-Marseille Université, 27 Boulevard Jean Moulin, Marseille 13385 CEDEX 5, France; Pôle des Maladies Infectieuses et Tropicales Clinique et Biologique, Fédération de Bactériologie-Hygiène-Virologie, Institut Hospitalo-Universitaire (IHU) Méditerranée Infection, Assistance Publique-Hôpitaux de Marseille, Marseille, France.
Abstract:
For several years, the threat of antibiotic resistance and its health cost has dramatically risen and various alarming figures have been proposed to illustrate the mortality due to antibiotic resistance. However, predictions concerning different living beings are doomed to failure, as theorised in Alice's 'living croquet' theory. Actors of antibiotic resistance are the doctors, the patient and the bacteria. Considering that animals and the environment are involved, future disasters are unpredictable. Here we evaluate in a rational manner the reliability of scientific sources showing increasing resistance to antibiotics or increasing mortality related to antibiotic resistance, and we finally consider antibiotic resources to face the situation.
Related Concept Videos
Antibiotic Selection
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Development of Antibiotic Resistance
Antimicrobial Effectiveness
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Urine Studies II: Urine Culture and Sensitivity Test

