Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electrocardiogram Fundamentals01:28

Electrocardiogram Fundamentals

1.7K
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
1.7K
Bode Plots Construction01:24

Bode Plots Construction

1.2K
The Bode plot is an essential tool in control system analysis, mapping the frequency response of a system through a magnitude plot and a phase plot, both against a logarithmic frequency axis. To construct a Bode plot, consider the transfer function H(ω):
1.2K
ECG Interpretation of Rhythms01:24

ECG Interpretation of Rhythms

16.6K
An electrocardiogram (ECG)graphically represents the heart's electrical activity on ECG paper or a monitor.
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
16.6K
Electrophoresis: Overview01:20

Electrophoresis: Overview

4.5K
Electrophoresis is a powerful analytical separation technique that relies on the differential migration of charged species when subjected to an electric field. The core strength of electrophoresis lies in its ability to separate high-molecular-weight species in complex mixtures. It has found widespread use in biochemistry, molecular biology, and analytical chemistry, allowing the separation of compounds like amino acids, nucleotides, carbohydrates, and proteins with excellent resolution.
There...
4.5K
Electrocardiogram01:29

Electrocardiogram

7.2K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
7.2K
Dysrhythmias III: Characteristics of Dysrhythmias01:29

Dysrhythmias III: Characteristics of Dysrhythmias

594
Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per...
594

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spotlight on EHRA 2026: illuminating arrhythmia management.

European heart journal·2026
Same author

Risk factors of atrial fibrillation progression in patients with congenital heart disease.

Clinical research in cardiology : official journal of the German Cardiac Society·2026
Same author

Mapping of atrial fibrillation: lessons learnt.

Indian pacing and electrophysiology journal·2026
Same author

High-power, very-high-power, and low-power radiofrequency ablation for atrial fibrillation: A Bayesian network meta-analysis.

Heart rhythm O2·2026
Same author

Long-term performance of conduction system pacing in patients with congenital heart disease.

Heart rhythm·2026
Same author

Ventricle-Specific Biomechanical Responses to Inotropic and Vasoactive Drugs in Human Myocardial Slices.

Journal of cardiovascular translational research·2026

Related Experiment Video

Updated: Mar 8, 2026

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

2.0K

Inhomogeneity and complexity in defining fractionated electrograms.

Lisette J M E van der Does1, Natasja M S de Groot1

  • 1Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Heart Rhythm
|January 21, 2017
PubMed
Summary

Current ablation strategies for atrial fibrillation are unsuccessful due to inconsistent definitions of complex fractionated atrial electrograms. Standardizing measurement methods is crucial for identifying true pathologic fractionation before further ablation attempts.

Keywords:
Atrial fibrillationCardiac electrophysiologyElectrogram fractionationMethodsPathophysiology

More Related Videos

Microstate and Omega Complexity Analyses of the Resting-state Electroencephalography
06:40

Microstate and Omega Complexity Analyses of the Resting-state Electroencephalography

Published on: June 15, 2018

10.8K
Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis
08:22

Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis

Published on: April 26, 2024

3.3K

Related Experiment Videos

Last Updated: Mar 8, 2026

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

2.0K
Microstate and Omega Complexity Analyses of the Resting-state Electroencephalography
06:40

Microstate and Omega Complexity Analyses of the Resting-state Electroencephalography

Published on: June 15, 2018

10.8K
Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis
08:22

Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis

Published on: April 26, 2024

3.3K

Area of Science:

  • Cardiac Electrophysiology
  • Medical Device Technology

Background:

  • Atrial fibrillation (AF) ablation strategies targeting complex fractionated atrial electrograms (CFAEs) have shown limited success.
  • Fractionation in atrial electrograms can stem from various pathologic and nonpathologic origins, complicating treatment.
  • A lack of standardized definitions hinders accurate identification of abnormal cardiac electrical activity.

Purpose of the Study:

  • To systematically review and analyze existing definitions and measurement methods for electrogram fractionation in human atrial electrophysiology.
  • To identify the diversity in definitions and parameters used to characterize CFAEs in scientific literature.
  • To highlight the need for a uniform approach to defining and measuring fractionation for improved AF treatment.

Main Methods:

  • A systematic literature search was conducted using PubMed for studies on human atrial electrophysiologic measurements describing fractionation.
  • Articles were screened for novel definitions of fractionation, automated detection programs, and measurement parameters.
  • Data on visual definitions, automated detection algorithms, measurement parameters, and continuous electrical activity definitions were extracted.

Main Results:

  • The search identified 348 articles, with 24 studies meeting the criteria.
  • These 24 studies presented 11 distinct visual definitions for fractionation, 3 automated CFAE detection programs, and 7 new measurement parameters.
  • Five different definitions for continuous electrical activity were also found, with electrode properties often poorly described.

Conclusions:

  • There is a significant lack of uniformity in definitions and recording methodologies for measuring cardiac atrial electrogram fractionation.
  • Varied electrophysiologic causes and the influence of recording device properties impede the identification of true pathologic inhomogeneous conduction.
  • Establishing consistent methods for identifying pathologic fractionation, potentially by correlating electrogram morphology with activation patterns, is essential before refining ablation strategies.