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Published on: August 23, 2024
CD44v6-Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells
Linxian Li1, Mark Schmitt2, Alexandra Matzke-Ogi2
1Institute of Toxicology and Genetics Karlsruhe Institute of Technology 76344 Karlsruhe Germany; Institute of Organic Chemistry University of Heidelberg 69120 Heidelberg Germany.
Abstract:
CD44v6 peptide functionalized nanoparticles are fabricated in a facile and controllable way to selectively bind to CD44v6 positive tumor cells with highly efficient anticancer and antimetastatic properties. The reported modular synthesis and facile preparation makes this system highly potent for developing novel multifunctional nanocarriers for therapeutic and/or diagnostic anticancer applications.

