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Disorders of the Male Reproductive System01:20

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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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A Promising Future for Prostate Cancer Diagnostics.

Stephen J Assinder1, Vanitha Bhoopalan2

  • 1Discipline of Physiology, School of Biomedical Sciences and Bosch Institute, University of Sydney, Sydney, NSW 2006, Australia. stephen.assinder@sydney.edu.au.

Diagnostics (Basel, Switzerland)
|January 21, 2017
PubMed
Summary

Early prostate cancer detection is crucial for better outcomes. Advances in imaging, biomarkers, and multi-disciplinary approaches are revolutionizing diagnostic platforms for this common male cancer.

Keywords:
223RaCl2PERCISTPI-RADS[18F]-NaF PET/CTcarbon nanotube technologiescirculating tumour cellsdiffusion weighted imagingoncosomal DNAs and RNAsoncosomesquantum dot multiplex arrays

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Area of Science:

  • Oncology and Urology
  • Medical Diagnostics

Background:

  • Prostate cancer incidence is rising globally with increasing life expectancy, disproportionately affecting aging males.
  • Current diagnostic methods often identify the disease late, after symptomatic presentation, impacting prognosis.
  • Early detection is paramount for effective management and improved patient outcomes.

Discussion:

  • This Special Issue reviews cutting-edge advancements in early prostate cancer diagnosis and prognosis.
  • Key areas explored include advanced imaging techniques like multiparametric MRI and novel biomaterials.
  • Emerging molecular biomarkers such as microRNAs and proteomics are discussed, alongside revolutionary diagnostic technologies.

Key Insights:

  • Multiparametric MRI protocols offer enhanced visualization for early detection.
  • MicroRNAs and proteomics represent promising avenues for molecular biomarker discovery.
  • Multi-disciplinary strategies are vital for developing accurate, accessible, and cost-effective diagnostic platforms.

Outlook:

  • Continued research into novel biomarkers and imaging will refine early detection capabilities.
  • Technological innovations are driving the development of more sophisticated diagnostic tools.
  • Integrated, multi-disciplinary approaches promise to deliver improved prostate cancer diagnostics globally.