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[Clinical studies on cefteram pivoxil in pediatrics]
M Yokoyama1, S Yonesaka, R Aoyama
1Department of Pediatrics, School of Medicine, Hirosaki University.
The Japanese Journal of Antibiotics
|August 1, 1989
Insights
Cefteram pivoxil, an oral cephem antibiotic, showed a 75% efficacy rate in treating infections in 16 children. This new antibiotic demonstrated no observed side effects or abnormal laboratory findings in the study participants.
Area of Science:
- Pharmacology
- Infectious Diseases
- Pediatrics
Context:
- The study evaluated a novel oral cephem antibiotic, cefteram pivoxil (CFTM-PI).
- CFTM-PI was administered to pediatric patients diagnosed with various infections.
Purpose:
- To assess the clinical efficacy and safety of cefteram pivoxil in children.
- To determine the treatment outcomes and adverse effects of CFTM-PI.
Summary:
- Cefteram pivoxil achieved a 75.0% clinical efficacy rate across 16 pediatric patients.
- Excellent or good clinical responses were observed in 12 out of 16 children.
- No adverse side effects or abnormal laboratory findings were reported during the treatment period.
Impact:
- Cefteram pivoxil presents a potentially safe and effective oral treatment option for pediatric infections.
- The findings support further investigation into CFTM-PI for broader clinical application in pediatric infectious disease management.
Abstract:
Cefteram pivoxil (CFTM-PI), a newly developed oral cephem antibiotic was administered to treat 16 children with various infections. The results were summarized as follows. 1. The clinical responses were "excellent" in 7, "good" in 5, "fair" in 3 and "poor" in 1, with 75.0% efficacy rate. 2. No side effects and no abnormal laboratory findings were observed.