Related Experiment Video
Updated: Mar 8, 2026

Monitoring Stub1-Mediated Pexophagy
Published on: May 12, 2023
Incredibly close-A newly identified peroxisome-ER contact site in humans
Maya Schuldiner1, Einat Zalckvar1
1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel maya.schuldiner@weizmann.ac.il einat.zalckvar@weizmann.ac.il.
Abstract:
Peroxisomes are tiny organelles that control important and diverse metabolic processes via their interplay with other organelles, including the endoplasmic reticulum (ER). In this issue, Costello et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607055) and Hua et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608128) identify a peroxisome-ER contact site in human cells held together by a tethering complex of VAPA/B (vesicle-associated membrane protein-associated proteins A/B) and ACBD5 (acyl Co-A binding protein 5).
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