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Updated: Mar 8, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
[Acute hemorrhage in the upper gastrointestinal tract]
M Busch1, A Schneider2, T Lankisch2
1Klinik für Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. busch.markus@mh-hannover.de.
Upper gastrointestinal (GI) bleeding is a common emergency with established treatments. However, high mortality persists due to serious comorbidities in affected patients.
Area of Science:
- Gastroenterology
- Emergency Medicine
- Internal Medicine
Background:
- Upper gastrointestinal (GI) bleeding represents a frequent and complex medical emergency.
- Established guidelines exist for acute medical, endoscopic, surgical, and radiological interventions.
Purpose of the Study:
- To highlight the challenges in managing upper GI bleeding.
- To underscore the impact of patient comorbidities on outcomes.
Main Methods:
- Review of existing treatment guidelines and protocols for upper GI bleeding.
- Analysis of factors contributing to mortality in upper GI bleeding cases.
Main Results:
- Despite comprehensive treatment options, mortality rates remain high.
- Preexisting serious illnesses in patients significantly contribute to adverse outcomes.
Conclusions:
- Effective management of upper GI bleeding requires addressing patient comorbidities.
- Further research may be needed to improve survival rates in complex cases.
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