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Updated: Mar 8, 2026

In vivo Evaluation of Mucociliary Clearance in Mice
Published on: December 18, 2020
A case study of ciliary detachment with primary pulmonary hypertension
Zhuolei Feng1, Li Dong2, Junxian Cao3
1Key Laboratory of Harbin Medical University Eye Center in Eye Hospital, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, Heilongjiang Province, 150001, People's Republic of China.
Purpose:
To introduce a case of ciliary detachment with primary pulmonary hypertension (PPH).
Methods:
The clinical manifestations of a case of ciliary detachment with PPH were addressed by comprehensive examination including ultrasound biological microscope (UBM), intraocular pressure, color fundus photographs, fluorescence fundus angiography (FFA). In addition, echocardiography is used to measure primary pulmonary pressure.
Results:
When the echocardiography displayed a systolic pulmonary arterial pressure of 106 mmHg, UBM exhibited ciliochoroidal detachment, as well as peripheral retinal effusion and non-perfusion areas in FFA. After well controlled of PPH, UBM showed normal ciliary body. FFA confirmed that retinal effusion disappeared.
Conclusions:
The elevated venous pressure in PPH is responsible for decreased choroidal backflow and reduced venous blood outflow from the eye. PPH would contribute to the clinical manifestations of severe choroidal detachment and peripheral retina effusion in this patient.
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