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Related Experiment Video

Updated: Mar 8, 2026

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
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Wire- and needle potentials facilitating transseptal puncture.

Konstantin M Heinroth1, Thomas Hartkopf1, Alexander Plehn1

  • 1Martin-Luther-University Halle-Wittenberg, Department of Medicine III.

Journal of Electrocardiology
|January 23, 2017
PubMed
Summary
This summary is machine-generated.

Intracardiac potentials from the transseptal puncture device can enhance safety during left heart interventions. These signals, recorded from the sheath-transseptal-needle/guidewire combination, provide reproducible information for guiding the procedure.

Keywords:
Far field potentialTransseptal punctureUnipolar intracardiac recording

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Area of Science:

  • Cardiology
  • Medical Devices
  • Electrophysiology

Background:

  • Transseptal puncture is a routine procedure for left heart interventions.
  • Current guidance relies on fluoroscopy and echocardiography.
  • Intracardiac potentials offer potential for enhanced procedural safety.

Purpose of the Study:

  • To investigate the utility of intracardiac potentials from the sheath-transseptal-needle/guidewire combination during transseptal puncture.
  • To assess if these signals can provide real-time procedural guidance.

Main Methods:

  • Recorded intracardiac potentials from the device in 31 patients undergoing transseptal puncture.
  • Utilized 3-D image integration for device visualization.
  • Analyzed signal morphology and amplitude changes at different locations.

Main Results:

  • Reproducible intracardiac potentials were derived in all patients.
  • Distinct signal changes identified the transition from the muscular interatrial septum to the fossa ovalis.
  • Signal amplitudes varied significantly between the septum and fossa ovalis in both sinus rhythm and atrial fibrillation.

Conclusions:

  • Typical changes in intracardiac signal morphology and amplitude can verify crucial steps of transseptal puncture.
  • This method is applicable in both sinus rhythm and atrial fibrillation.
  • Intracardiac potentials enhance the safety and guidance of transseptal procedures.