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Updated: Mar 8, 2026

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract
Published on: November 28, 2012
Radiation Cataractogenesis: The Progression of Our Understanding and Its Clinical Consequences
Danyal Zaman Khan1, Marie Constance Lacasse2, Rizwana Khan1
1Royal College of Surgeons, Dublin, Ireland.
Abstract:
In the high-volume and increasingly complex world of image-guided therapy and medical imaging, awareness of the potential risks secondary to occupational radiation exposure in medical professionals needs greater focus. One of these risks is radiation-induced cataracts, a recently recognized entity, which may impact the physician's professional proficiency, quality of life, and career span. This review article aims to explain the pathogenesis of radiation-induced cataracts, exploring emerging evidence regarding their development. It also explores the existing monitoring and protection measures available to protect against such radiation-induced pathologic conditions.
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