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Synthesis, Surface and Antimicrobial Activity of Piperidine-Based Sulfobetaines
Daria Wieczorek1, Adam Dobrowolski2, Katarzyna Staszak3
1Department of Technology and Instrumental Analysis, Faculty of Commodity Science, Poznan University of Economics and Business, al. Niepodległości 10, 61-875 Poznan, Poland.
Abstract:
A new method for the preparation of new heterocyclic amine surfactants based on sulfobetaines is proposed. Interfacial activities of the surfactants obtained in aqueous solution were studied by surface tension measurements. The critical micelle concentration, surface excess concentration, minimum area per surfactant molecule, and standard Gibbs energy of adsorption were determined. The adsorption properties of these compounds depend significantly on the alkyl chain length. Alkyl chain length also affects biological properties of the new surfactants, determining the minimum inhibitory concentration and size of inhibited growth zone. The compounds have high antimicrobial activity.
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