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Updated: Aug 8, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
[Experience in the differential diagnosis of infectious diseases]
Abstract:
It is stated that social and scientific progress in the course of evolution gives rise to marked changes in infectious pathology. The changes are obvious from reduced incidence of epidemic diseases, distinct clinical appearance of infection, different cyclic pattern of a number of nosological entities. Such newly recognized diseases as hemorrhagic fever, adenovirus and herpes virus infections, yersiniosis, rotavirus gastroenteritis, legionellosis, AIDS have advanced to the forefront. Previously unknown affections are likely to emerge in various areas of the world and become prevalent in extreme conditions. In addition to virological and immunological examinations, differential diagnosis of the above infections should include a comprehensive analysis of medical histories and clinicoepidemiological evidence in order to provide early detection, hospitalization, high therapeutic response.
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