Related Experiment Video
Updated: Mar 8, 2026

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
Published on: September 16, 2020
Transient cortical blindness after intradiscal oxygen-ozone therapy
Agostino Salvatore Vaiano1, Cristiana Valente1, Giacomo De Benedetti2
1Struttura Complessa di Oculistica, Azienda Ospedaliera Santa Croce e Carle di Cuneo, Cuneo, Italy.
Abstract:
A 54-year-old caucasian male developed bilateral blindness during an oxygen-ozone injection for disc herniation. The visual loss (VL) was immediately followed by severe frontal headache, vomiting, and nausea. The patient underestimated the VL showing Anton's syndrome, with a complete visual recovery after 2-month follow-up. Magnetic resonance data were consistent with recent ischemic lesions in bilateral vascular territories of posterior cerebral arteries.

