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Published on: November 30, 2010
[Surgical site infections in children undergoing cardiac surgery with delayed sternal closure: Case-control study]
Javiera Retamal1, Pedro Becker2, Rodrigo González2
1División de Pediatría, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile, claveria@med.puc.cl.
Insights
Prolonged cardiopulmonary bypass and mechanical ventilation are key risk factors for surgical site infections (SSI) in pediatric cardiac surgery patients requiring delayed sternal closure. Identifying these factors aids in preventing post-operative complications.
Area of Science:
- Pediatric Cardiac Surgery
- Infectious Disease Epidemiology
- Surgical Outcomes
Background:
- Surgical site infections (SSI) are a significant cause of morbidity in pediatric cardiac surgery.
- Risk factors for SSI in patients undergoing delayed sternal closure (DSC) are not well-established.
Purpose of the Study:
- To determine the incidence of SSI in pediatric cardiac surgery patients with DSC.
- To identify independent risk factors associated with SSI in this patient population.
Main Methods:
- Retrospective case-control study of pediatric patients (<15 years) undergoing cardiac surgery with DSC (2009-2010).
- SSI diagnosis based on institutional criteria aligned with international recommendations.
- Univariate and multivariate analyses were performed to identify risk factors (p < 0.05).
Main Results:
- 58 patients were analyzed; 13 (22%) developed SSI (11 incisional, 2 mediastinitis).
- Independent risk factors for SSI included bypass (BP) time > 200 minutes (OR 9.53) and mechanical ventilation (MV) > 5 days (OR 8.98).
Conclusions:
- Extended bypass time and prolonged mechanical ventilation are significant risk factors for SSI in pediatric cardiac surgery patients with DSC.
- These findings highlight critical areas for intervention to reduce SSI rates.
Introduction:
Surgical site infections (SSI) are an important cause of morbidity in pediatric cardiac surgery. Risk factors in patients requiring delayed sternal closure (DSC) are unknown.
Aim:
To report the rate of SSI in children undergoing cardiac surgery with DSC and determine the risk factors.
Methodology:
A retrospective case-control study, in patients younger than 15 years old undergoing cardiac surgery with DSC in our center between 2009 and 2010. SSI was diagnosed according to the criteria of the nosocomial infections committee of our institution, based on international recommendations. Univariate and multivariate analysis of variables was performed. A p < 0.05 was considered significant.
Results:
58 patients were included; the average age was 9.5 days. The most frequent diagnosis were transposition of the great arteries (36%) and hypoplastic left heart syndrome (27%). 13 patients had SSI (22%); 11 incisional and 2 mediastinitis. It was independently associated to SSI by-pass (BP) time longer than 200 min (OR adjusted = 9,53; IC 95% 1,37-66,35) and mechanical ventilation (MV) more than 5 days (OR adjusted = 8,98; IC 95% 1,16-69,40).
Conclusion:
The duration of BP and MV are risk factors of SSI in children undergoing cardiac surgery with DSC.
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