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A reusable adapter for collection of cerebrospinal fluid in chronically cannulated goats
V A Forte1, J A Devine, A Cymerman
1U.S. Army Research Institute of Environmental Medicine, Altitude Research Division, Natick, MA 01760.
Laboratory Animal Science
|September 1, 1989
Abstract:
A lightweight, adjustable adapter has been designed for chronic cannulation of goats (Capra hircus) which provides an accurate, safe means of sampling cerebrospinal fluid (CSF). This cisternal cannula has been used for continuous perfusion of synthetic CSF into the fourth ventricle in unanesthetized goats. This method also has been used for examining changes in ionic composition of the CSF and cerebral interstitial fluid (ISF) during physiologic adaptations to high altitude (2-5).