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Complications of Uveitis: The Northern California Epidemiology of Uveitis Study
David C Gritz1,2,3,4, Eric J Schwaber5, Ira G Wong1,2,6
1a Francis I. Proctor Foundation for Research in Ophthalmology, San Francisco, California, USA.
Purpose:
To describe the uveitis complications in a large, community-based cohort.
Methods:
Retrospective, community-based, cross-sectional cohort study analyzing complications and associations with complications.
Results:
A total of 844 cases of uveitis were found; 342 were new-onset, and 462 were prior-onset. In total, 29.5% of patients were affected by one or more complications associated with age, gender, course, and anatomic location of uveitis. Visual loss was experienced by 19.1% of patients and was associated with age, course of disease, and anatomic location of uveitis. Of the patients who developed glaucoma or elevated intraocular pressure over 30 mmHg, 3.9% (n = 33) were related solely to uveitis; 5.2% (n = 44) had an unclear or combined mechanism; and 1.8% (n = 15) were related solely to steroid response. Cystoid macular edema was associated with course of disease and anatomic location of uveitis.
Conclusions:
Complications affect a significant portion of uveitis patients, and are often associated with demographic and clinical factors.
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