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PSMA Uptake in Mediastinal Sarcoidosis
Philip Junior Ardies1, Pieterjan Gykiere, Lode Goethals
1From the *Department of Nuclear Medicine, and †Department of Radiology, University Hospital Brussel; and ‡∥Department of Nuclear Medicine, AZ Sint-Jan Brugge-Oostende, Belgium.
Clinical Nuclear Medicine
|January 24, 2017
Summary
Gallium-PSMA PET/CT scans show increased uptake in thoracic lymph nodes due to sarcoidosis, not just prostate cancer. Recognizing this finding is crucial for accurate diagnosis and avoiding misinterpretation in patients undergoing PSMA imaging.
Area of Science:
- Nuclear medicine
- Oncology
- Radiology
Background:
- Prostate-specific membrane antigen (PSMA) is a key biomarker overexpressed in prostate cancer.
- Gallium-PSMA PET/CT is a vital tool for prostate cancer management.
- PSMA expression is not exclusive to prostate cancer, appearing in other malignancies and benign conditions.

