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Changes in monoamines and their metabolite levels in substantia nigra of aged rats
J L Venero1, A Machado, J Cano
1Departmento de Bioquimica, Facultad de Farmacia, Sevilla, Spain.
Mechanisms of Ageing and Development
|September 1, 1989
Abstract:
A decrease in the monoamine and monoamine metabolite contents in the substantia nigra of aged rats vs. controls has been found. Hence, it can be speculated that this decrease may play a role in the multiple alterations in dopaminergic functions observed in aged rats.