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A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
Commentary: Reconsidering the Role of Context in Diabetes Prevention
Briana Mezuk1, Jeannie B Concha2, Paul Perrin3
1Department of Family Medicine, Virginia Commonwealth University School of Medicine.
Abstract:
A substantial gap remains between what we know about type 2 diabetes prevention and our ability to apply that knowledge in socially disadvantaged populations at highest risk. This gap results, in part, from a lack of integration between epidemiologic science and social psychology theory, particularly regarding the intersections of stress, self-regulatory health behaviors, and the biological mechanisms underlying the development of diabetes. In this commentary, we describe the utility of a theoretical framework that focuses on the intersection of biological, psychosocial, and environmental contexts as they apply to diabetes disparities, and how such a framework could inform a translational research agenda to reorient prevention efforts to address these inequalities. Such reorientation is needed to ensure that the implementation of prevention efforts does not inadvertently widen diabetes disparities.
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