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Updated: Mar 8, 2026

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
Published on: March 7, 2025
The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches
Pankita H Pandya1, Mary E Murray2, Karen E Pollok3
1Indiana University School of Medicine, Riley CCRC 2641, 705 Riley Hospital Drive, Indianapolis, IN 46202, USA.
Abstract:
Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the fundamentals of incorporating precision medicine to discover new immune biomarkers and predictive signatures. Using a personalized approach may have a significant, positive impact on the use of oncolytics to better guide safer and more effective therapies.
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