Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Effects of Radiation02:59

Biological Effects of Radiation

18.6K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
18.6K
Interaction of EM Radiation with Matter: Spectroscopy01:12

Interaction of EM Radiation with Matter: Spectroscopy

3.7K
Electromagnetic (EM) radiation can be considered an oscillating electric and magnetic field propagating through a medium that can interact with matter in its path. The electric field in the radiation can interact with electrical charges in the atoms or molecules in the matter. On the other hand, the magnetic field can interact with the magnetic field in the atomic nucleus. The study of the interaction between electromagnetic radiation and matter is termed spectroscopy. Spectroscopy is the study...
3.7K
Mutations01:35

Mutations

45.0K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
45.0K
Radiation: Applications01:17

Radiation: Applications

1.9K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
1.9K
Absorption of Radiation01:05

Absorption of Radiation

1.4K
The rate of heat transfer by emitted radiation is described by the Stefan-Boltzmann law of radiation:
1.4K
Isotopes and Radioisotopes01:28

Isotopes and Radioisotopes

13.4K
In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically indistinguishable. These different types are called isotopes — atoms of the same element that differ in mass. Isotopes differ in mass because they have different numbers of neutrons but are chemically identical because they have the same number of protons. Soddy was awarded the Nobel Prize in Chemistry in 1921 for this discovery.
An isotope containing...
13.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gallic Acid-Mediated Enhancement of Diazepam-Induced Sedation via GABA<sub>A</sub> Receptor Modulation: In Vivo and In Silico Evaluation.

Food science & nutrition·2026
Same author

Probiotics, synbiotics and berberine in Type 2 diabetes mellitus: A systematic review, meta-analysis, and molecular dynamics simulation study.

PloS one·2026
Same author

Lenalidomide ameliorates cognitive impairment via putative AChE inhibition: an in silico and in vivo study in a scopolamine-induced cognitive impairment model.

Scientific reports·2026
Same author

Correction to: Sedative effects of physcion and its modulatory interaction with diazepam: in vivo and in silico evaluation.

Naunyn-Schmiedeberg's archives of pharmacology·2026
Same author

Anticonvulsant Effects of Citronellal, Daidzin, and Phytol, Possibly Through GABA<sub>A</sub> Receptor and Voltage-Gated Sodium Channel Interaction Pathways: In Vivo and In Silico Studies.

Brain and behavior·2026
Same author

Antidiarrheal Potential of Psoralidin Through Modulation of COX, μ-Opioid, and L-Type Calcium Channel Signaling Pathways: In Vivo and In Silico Investigations.

Neurogastroenterology and motility·2026

Related Experiment Video

Updated: Mar 8, 2026

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments
06:08

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments

Published on: May 26, 2019

8.0K

Radiation interactions with biological systems.

Muhammad Torequl Islam1,2

  • 1a Postgraduate Program in Biotechnology, Northeast Biotechnology Network (RENORBIO) , Federal University of Piauí , Teresina (Paiui) , Brazil.

International Journal of Radiation Biology
|January 25, 2017
PubMed
Summary

Ionizing radiation (IR) has dual effects in biology, causing oxidative stress that can be beneficial or harmful. Understanding these mechanisms is crucial for medical applications of IR.

Keywords:
Ionizing radiationoxidative stressphysiological effectsreactive oxygen species

More Related Videos

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis
07:08

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Published on: August 31, 2022

2.1K
Irradiator Commissioning and Dosimetry for Assessment of LQ &#945; and &#946; Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.8K

Related Experiment Videos

Last Updated: Mar 8, 2026

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments
06:08

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments

Published on: May 26, 2019

8.0K
Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis
07:08

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Published on: August 31, 2022

2.1K
Irradiator Commissioning and Dosimetry for Assessment of LQ &#945; and &#946; Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.8K

Area of Science:

  • Medical Sciences
  • Radiation Biology
  • Cellular Physiology

Background:

  • Ionizing radiation (IR) is widely used in medical sciences.
  • IR exhibits both beneficial and detrimental effects on biological systems.
  • A mechanistic understanding of IR's physiological impact is needed.

Purpose of the Study:

  • To elucidate the mechanistic pathways of ionizing radiation-mediated physiological events.
  • To review the dual role of IR in biological systems.

Main Methods:

  • Literature review of evidence from PubMed and Science Direct databases.
  • Focus on mechanistic aspects of IR effects.

Main Results:

  • IR induces oxidative stress, both directly and indirectly.
  • Harmful effects include aging, genetic instability, cell death, and cancer.
  • IR can impair DNA repair, increasing radiosensitivity.

Conclusions:

  • The biological effects of IR are dose, duration, and quality-dependent.
  • IR plays diverse roles in biological systems, necessitating careful application.