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Updated: Mar 8, 2026

Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
Novel Isoprene Sensor for a Flu Virus Breath Monitor
Pelagia-Irene Gouma1,2, Lisheng Wang3, Sanford R Simon4
1Department of Materials Science & Engineering & IPPM-UTARI, University of Texas at Arlington, Arlington, TX 76019, USA. pelagia.gouma@uta.edu.
Abstract:
A common feature of the inflammatory response in patients who have actually contracted influenza is the generation of a number of volatile products of the alveolar and airway epithelium. These products include a number of volatile organic compounds (VOCs) and nitric oxide (NO). These may be used as biomarkers to detect the disease. A portable 3-sensor array microsystem-based tool that can potentially detect flu infection biomarkers is described here. Whether used in connection with in-vitro cell culture studies or as a single exhale breathalyzer, this device may be used to provide a rapid and non-invasive screening method for flu and other virus-based epidemics.
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