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Acute Cerebral Infarction as a Rare Thrombotic Event in Myelodysplastic Syndrome: A Case Report

Hyun Woo Bae1, Hyun Dong Kim1, Sung Won Choi1

  • 1Department of Physical Medicine and Rehabilitation, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

Annals of Rehabilitation Medicine
|January 26, 2017
PubMed

Insights

This study reports a rare case of acute cerebral infarction in a patient with Myelodysplastic Syndrome (MDS). The infarction, a type of stroke, may be linked to the complex genetic and inflammatory factors associated with MDS.

Area of Science:

  • Hematology
  • Neurology
  • Oncology

Background:

  • Myelodysplastic syndrome (MDS) is a bone marrow failure disorder.
  • MDS commonly presents with cytopenia, increasing risks of infection and bleeding.
  • Cerebral infarction is an uncommon complication reported in MDS patients.

Purpose of the Study:

  • To report a rare case of acute cerebral infarction in a patient diagnosed with Myelodysplastic Syndrome.
  • To discuss potential underlying mechanisms contributing to arterial thrombosis in MDS.

Main Methods:

  • Case report of a 72-year-old female patient with MDS.
  • Review of clinical history, focusing on stroke risk factors.
  • Analysis of potential contributing factors for cerebral infarction in the context of MDS.

Main Results:

  • The patient, with no significant stroke risk factors besides controlled diabetes and dyslipidemia, developed acute cerebral infarction.
  • This case highlights a rare instance of arterial thrombosis leading to stroke in an MDS patient.

Conclusions:

  • Arterial thrombosis causing cerebral infarction is a rare but possible complication of Myelodysplastic Syndrome.
  • Complex chromosomal abnormalities and inflammatory processes in MDS may contribute to the risk of stroke.
Keywords:
Myelodysplastic syndromesStrokeThrombosis

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