Related Experiment Video
Updated: Mar 8, 2026

Analysis of Lipid Droplet Content in Fission and Budding Yeasts using Automated Image Processing
Published on: July 17, 2019
Budding Yeast: An Ideal Backdrop for In vivo Lipid Biochemistry
1Center for Cell Dynamics, Department of Cell Biology, Johns Hopkins University School of MedicineBaltimore, MD, USA; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins UniversityBaltimore, MD, USA.
Abstract:
Biological membranes are non-covalent assembly of lipids and proteins. Lipids play critical role in determining membrane physical properties and regulate the function of membrane associated proteins. Budding yeast Saccharomyces cerevisiae offers an exceptional advantage to understand the lipid-protein interactions since lipid metabolism and homeostasis are relatively simple and well characterized as compared to other eukaryotes. In addition, a vast array of genetic and cell biological tools are available to determine and understand the role of a particular lipid in various lipid metabolic disorders. Budding yeast has been instrumental in delineating mechanisms related to lipid metabolism, trafficking and their localization in different subcellular compartments at various cell cycle stages. Further, availability of tools and enormous potential for the development of useful reagents and novel technologies to localize a particular lipid in different subcellular compartments in yeast makes it a formidable system to carry out lipid biology. Taken together, yeast provides an outstanding backdrop to characterize lipid metabolic changes under various physiological conditions.
More Related Videos
08:56Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
Published on: March 8, 2020
08:43A Quantitative Assessment of The Yeast Lipidome using Electrospray Ionization Mass Spectrometry
Published on: August 21, 2009
Related Concept Videos
Biosynthesis of Lipids
Yeast Signaling
Lipid Catabolism
Formation of Lipopolysaccharides
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...