Targeting a metabolic pathway to fight the flu
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Updated: Mar 8, 2026

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
Published on: June 28, 2013
Yvonne Boergeling1, Stephan Ludwig1
1Institute of Virology (IVM), Westfaelische-Wilhelms University, Muenster, Germany.
Abstract:
Our antiviral arsenal to fight influenza viruses is limited and we need novel anti-flu drugs. Recently, cellular drug targets came into focus and omics analysis were instrumental to suggest candidate factors. In this issue of The FEBS Journal, Kainov and colleagues used transcriptome data to investigate virus-induced changes in tryptophan metabolism that may serve as immunomodulatory approach against viruses.
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