Related Experiment Video
Updated: Mar 8, 2026
Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
Published on: March 13, 2015
Serum C-reactive protein predicts early mortality in hospitalized patients with HBV-related decompensated cirrhosis
ShaoMing Zhu1, Yulituzi Waili, XiaoTing Qi
1Department of Ultrasonography, the First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang Department of Clinical Laboratory, The Sixth Affiliated Hospital of Xinjiang Medical University, Xinjiang Department of Clinical Laboratory, The People's Hospital of Xinjiang Uygur Autonomous Region, Tianshan District, Urumqi Department of Clinical Laboratory Department of Hand Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang, China.
Abstract:
The serum C-reactive protein (CRP) is an inflammatory marker. The aim of the present study was to elucidate whether CRP could serve as a potential surrogate marker for 30-day mortality in hospitalized patients with HBV-related decompensated cirrhosis (HBV-DeCi).This was a retrospective cohort study that included 140 patients with HBV-DeCi. All patients were followed up for 1-month. A panel of clinical and biochemical variables were analyzed for potential associations with outcomes using multiple regression models.The serum CRP was significantly higher in nonsurviving patients than in surviving patients. Multivariate analysis demonstrated that CRP levels (odds ratio: 1.047, P = 0.002) and the model for end-stage liver disease score (odds ratio: 1.370, P = 0.001) were independent predictors for mortality.Serum CRP is a simple marker that may serve as an additional predictor of 1-month mortality in hospitalized patients with HBV-DeCi.
