Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

2.2K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
2.2K
Plasticity00:58

Plasticity

3.2K
Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experience dependent plasticity of higher visual cortical areas in the mouse.

Cerebral cortex (New York, N.Y. : 1991)·2023
Same author

Recruitment of frontal sensory circuits during visual discrimination.

Cell reports·2022
Same author

RPG: A low-cost, open-source, high-performance solution for displaying visual stimuli.

Journal of neuroscience methods·2021
Same author

Stable Encoding of Visual Cues in the Mouse Retrosplenial Cortex.

Cerebral cortex (New York, N.Y. : 1991)·2020
Same author

Top-Down Suppression of Sensory Cortex in an NMDAR Hypofunction Model of Psychosis.

Schizophrenia bulletin·2019
Same author

Behavioral training rescues motor deficits in Cyfip1 haploinsufficiency mouse model of autism spectrum disorders.

Translational psychiatry·2019

Related Experiment Video

Updated: Mar 8, 2026

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

11.4K

Stability and Plasticity of Contextual Modulation in the Mouse Visual Cortex.

Adam Ranson1

  • 1Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, CF24 4HQ, UK.

Cell Reports
|January 26, 2017
PubMed
Summary

The mature visual cortex has stable neuron networks for sensory and movement contexts. Less active neurons show more plasticity, adapting to visual experiences over time.

Keywords:
locomotionplasticitysize tuningvisual cortex

More Related Videos

A Highly Reproducible and Straightforward Method to Perform In Vivo Ocular Enucleation in the Mouse after Eye Opening
05:29

A Highly Reproducible and Straightforward Method to Perform In Vivo Ocular Enucleation in the Mouse after Eye Opening

Published on: October 6, 2014

24.6K
Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus
05:01

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Published on: September 20, 2024

841

Related Experiment Videos

Last Updated: Mar 8, 2026

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

11.4K
A Highly Reproducible and Straightforward Method to Perform In Vivo Ocular Enucleation in the Mouse after Eye Opening
05:29

A Highly Reproducible and Straightforward Method to Perform In Vivo Ocular Enucleation in the Mouse after Eye Opening

Published on: October 6, 2014

24.6K
Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus
05:01

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Published on: September 20, 2024

841

Area of Science:

  • Neuroscience
  • Visual Cortex Research
  • Neural Plasticity

Background:

  • Neuronal activity in the primary visual cortex is influenced by sensory and behavioral context.
  • The long-term stability of these contextual influences in the mature brain is not well understood.

Purpose of the Study:

  • To investigate the long-term stability of surround suppression and locomotion influences on individual neurons in the mature visual cortex.
  • To differentiate neuronal responses based on activity level and cell type.

Main Methods:

  • Utilized two-photon calcium imaging to monitor neuronal activity over 14 days.
  • Tracked the modulation of individual neurons by visual context (surround suppression) and locomotion.

Main Results:

  • Highly active excitatory neurons and parvalbumin-positive (PV+) interneurons showed stable modulation by visual context.
  • Most neurons displayed stable, distinct modulation by locomotion.
  • Less active excitatory neurons demonstrated plasticity, with increased suppression in response to visual context.

Conclusions:

  • The mature visual cortex contains stable neuronal subnetworks with consistent interactions with sensory and behavioral contexts.
  • Neuronal cell type and activity level determine the stability of contextual modulation.
  • Less active neurons are more plastic and sensitive to visual experience, indicating ongoing adaptation.