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Role of neurotrophic factors in Alzheimer's disease
K S Chen1, M H Tuszynski, F H Gage
1Department of Neurosciences, University of California, San Diego, La Jolla 92093.
Neurobiology of Aging
|September 1, 1989
Abstract:
Neurotrophic factors (NTFs) could potentially play a role in Alzheimer's disease (AD) in many ways. Neuronal degeneration may result from disruption in NTF production, delivery, or interaction with the neuronal target. Even if alterations in NTF function are not responsible for neuronal degeneration, NTFs may still be therapeutically useful in ameliorating some morphological or cognitive deficits observed in AD.