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Radiologic long-term results after cervical vertebral interbody fusion with polymethyl methacrylat (PMMA)
D K Böker1, R Schultheiss, E M Probst
1Department of Neurosurgery, University of Bonn, West Germany.
Abstract:
Long-term results of cervical interbody fusion with PMMA were evaluated in a retrospective study. X-ray films of 83 patients were obtainable. Post-operative follow-up in this series was between 15 and 20 years. The results show that PMMA is engrafted after about 2 years. Stable vertebral interbody fusion is obtained in about 90% of cases. Development of malignoma was not observed. Resorptive bone alterations, which can be seen in about 2% of cases one to two years after operation are shown not to be progressive. This process heals and stable fusion develops.
Insights
Long-term cervical interbody fusion with polymethyl methacrylate (PMMA) shows excellent results. This study found PMMA is engrafted in about 2 years, achieving stable fusion in 90% of patients with no observed malignoma.
Area of Science:
- Orthopedics
- Spinal Surgery
- Biomaterials
Background:
- Cervical interbody fusion is a common surgical procedure.
- Polymethyl methacrylate (PMMA) has been used as a bone graft substitute.
- Long-term outcomes of PMMA in cervical fusion require further evaluation.
Purpose of the Study:
- To evaluate the long-term efficacy and safety of cervical interbody fusion using PMMA.
- To assess bone engraftment, fusion stability, and potential complications.
Main Methods:
- Retrospective study of 83 patients undergoing cervical interbody fusion with PMMA.
- Radiographic assessment of bone engraftment and fusion stability.
- Long-term follow-up ranging from 15 to 20 years post-operation.
Main Results:
- Polymethyl methacrylate (PMMA) demonstrated engraftment by approximately 2 years post-surgery.
- Stable vertebral interbody fusion was achieved in about 90% of the evaluated cases.
- No instances of malignoma development were observed; resorptive bone alterations were non-progressive and healed, occurring in only 2% of cases.
Conclusions:
- Cervical interbody fusion with PMMA is a safe and effective long-term solution.
- PMMA provides stable fusion and does not increase the risk of malignancy.
- Observed bone alterations are transient and do not compromise fusion stability.