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Does abstinence resolve poor sleep quality in former methamphetamine dependents?

Amir Rezaei Ardani1, Seyyed Ali Saghebi1, Mahsa Nahidi1

  • 1Psychiatry and Behavioural Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Sleep Science (Sao Paulo, Brazil)
|January 27, 2017
PubMed
Abstract

Insights

Sleep quality significantly improves for methamphetamine-dependent patients after four weeks of abstinence. This improvement in sleep quality during early remission is largely independent of changes in anxiety and depressive symptoms.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Sleep Medicine

Background:

  • Stimulants like amphetamines significantly impact sleep.
  • Limited research exists on sleep quality during methamphetamine withdrawal.

Purpose of the Study:

  • To evaluate changes in sleep quality in methamphetamine-dependent patients during early remission.
  • To control for depression and anxiety as potential confounding variables affecting sleep quality.

Main Methods:

  • Ninety methamphetamine-dependent patients in residential centers were assessed.
  • Sleep quality was measured using the Pittsburgh Sleep Quality Questionnaire at weeks 1, 2, and 4 of abstinence.
  • Depression and anxiety were assessed using Beck Depression Inventory-2 and Beck Anxiety Inventory.

Main Results:

  • The prevalence of poor sleep quality decreased from 97.8% in the first week to 52.2% at four weeks post-abstinence (P=0.00).
  • Variations in depression and anxiety had a minimal impact on sleep quality changes (adjusted R2<0.5).
  • The influence of anxiety and depression on sleep quality diminished over time.

Conclusions:

  • Methamphetamine withdrawal patients experience significant sleep quality improvement after four weeks of abstinence.
  • Sleep quality improvement during early remission is independent of concurrent changes in anxiety and depressive symptoms.
Keywords:
AbstinenceAmphetamineAnxietyDepressionSleep quality

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