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Updated: Mar 8, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
Catheter directed interventions for acute deep vein thrombosis
Maureen P Kohi1, Ryan Kohlbrenner1, Kanti P Kolli1
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.
Venous thromboembolism (VTE), including deep vein thrombosis (DVT), affects many patients globally. This review covers treatments for acute DVT, emphasizing catheter-directed interventions to prevent post-thrombotic syndrome (PTS).
Area of Science:
- Vascular Medicine
- Interventional Cardiology
- Thrombosis Research
Background:
- Venous thromboembolism (VTE) is a prevalent vascular condition affecting numerous patients worldwide.
- Acute deep vein thrombosis (DVT), a form of VTE, is typically managed with anticoagulation.
- Emerging evidence supports catheter-directed interventions for acute DVT to mitigate post-thrombotic syndrome (PTS) risk.
Purpose of the Study:
- To review current and novel therapeutic strategies for acute deep vein thrombosis (DVT).
- To focus on the role and efficacy of catheter-directed interventions in managing acute DVT.
- To explore the potential of these interventions in reducing the incidence of post-thrombotic syndrome (PTS).
Main Methods:
- Comprehensive literature review of therapies for acute deep vein thrombosis (DVT).
- Analysis of data supporting catheter-directed interventions versus traditional anticoagulation.
- Discussion of various thrombectomy techniques, including aspiration thrombectomy.
Main Results:
- Anticoagulation remains a traditional treatment for acute deep vein thrombosis (DVT).
- Catheter-directed interventions show promise in reducing post-thrombotic syndrome (PTS) following acute DVT.
- Novel aspiration thrombectomy techniques offer advanced options for clot removal.
Conclusions:
- Catheter-directed interventions represent a significant advancement in managing acute deep vein thrombosis (DVT).
- These minimally invasive techniques aim to improve outcomes by reducing the long-term complication of post-thrombotic syndrome (PTS).
- The review highlights the evolving landscape of DVT treatment, from anticoagulation to advanced thrombectomy methods.
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