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Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
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Femoral impaction bone grafting with the Elite Plus stem.
D E Robinson1, M B Lee, V A Smith
1Avon Orthopaedic Centre, Southmead Hospital, Westbury-on-Trym, Bristol - UK.
Summary
Impaction grafting using the Elite Plus system for revision hip arthroplasty showed a high failure rate, particularly in patients with significant bone loss. Graft incorporation was limited, with poor bone remodeling observed in this study.
Area of Science:
- Orthopedic Surgery
- Biomaterials Science
Background:
- Revision hip arthroplasty is complex, often requiring bone reconstruction.
- Impaction grafting with allograft is a technique used to address bone stock defects.
- The Elite Plus system is one option for femoral stem implantation in revision cases.
Purpose of the Study:
- To evaluate the outcomes of impaction grafting with the Elite Plus femoral stem.
- To assess graft incorporation and bone healing after revision hip arthroplasty.
- To determine the failure rate and complications associated with this technique.
Main Methods:
- A prospective study of 19 hips undergoing revision hip arthroplasty.
- Utilized the Elite Plus femoral stem with irradiated allograft for impaction grafting.
- Patients were followed for an average of 33 months with radiographic and clinical assessments.
- Bone stock loss was graded using the Endo-Klinik classification.
Main Results:
- Graft incorporation was observed in 32% of cases.
- No significant trabecular remodeling or cortical repair was evident radiographically.
- A high failure rate was noted, with 4 patients requiring revision surgery.
- Complications were more frequent in patients with Endo-Klinik grade 3 bone loss.
Conclusions:
- Impaction grafting with the Elite Plus system demonstrated a high failure rate in revision hip arthroplasty.
- The technique appears less successful in patients with substantial bone stock loss.
- Further research is needed to improve outcomes for complex revision hip surgeries.

