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Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
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Biomarker-Guided Non-Adaptive Trial Designs in Phase II and Phase III: A Methodological Review

Miranta Antoniou1,2, Ruwanthi Kolamunnage-Dona3,4, Andrea L Jorgensen5,6

  • 1MRC North West Hub for Trials Methodology Research, Liverpool L69 3GL, UK. Miranta.Antoniou@liverpool.ac.uk.

Journal of Personalized Medicine
|January 27, 2017
PubMed

Keywords:
biomarker-guided trial designclinical research designclinical trials methodologynon-adaptive trial designspersonalized medicinephase IIphase IIIpredictive biomarkerprognostic biomarkersample size

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