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Updated: Mar 8, 2026

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
Published on: February 16, 2020
Shuttle Catalysis-New Strategies in Organic Synthesis
Benjamin N Bhawal1, Bill Morandi1
1Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470, Mülheim an der Ruhr, Germany.
Abstract:
Shuttle catalysis has recently emerged as a powerful new concept that provides a platform for performing both functionalization and defunctionalization reactions. In this concept article, applications of shuttle catalysis as a novel strategy in organic synthesis are discussed. This includes using forward shuttle catalysis reactions for challenging bond-forming processes that avoid the use of hazardous chemicals. Shuttle catalysis also facilitates the transfer of reactive functionality as a route to procure a broad range of compounds using one simple procedure. Reverse shuttle catalysis reactions are also discussed as a method for the valorization of biomass and waste materials. Another area of interest, shuttle-catalysis-assisted reactions, wherein the transfer of a small molecule is utilized in a catalytic cycle, is also described. Possible future directions in this exciting new field are also suggested.
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