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THA and TKA in patients with cardiovascular disease: What makes the risk of perioperative bleeding?
Insights
Patients with cardiac disease undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA) face a higher risk of bleeding complications. These complications are more frequent after THA and TKA compared to other surgeries, even after adjusting for risk factors.
Area of Science:
- Orthopedic Surgery
- Cardiology
- Thromboembolic Disease Management
Background:
- Patients with cardiac disease have complex perioperative needs.
- Thromboembolic disease poses significant risks in surgical patients.
- Understanding complication rates after major joint replacement is crucial for patient safety.
Purpose of the Study:
- To determine the incidence of bleeding and ischemic complications.
- To compare complication rates after total hip arthroplasty (THA) and total knee arthroplasty (TKA) in cardiac patients.
- To evaluate complication risks relative to other musculoskeletal surgeries.
Main Methods:
- Retrospective study of 477 patients with cardiac disease undergoing THA or TKA between 2010-2013.
- All patients received perioperative prevention of thromboembolic disease with low-molecular-weight heparins.
- Data collection focused on perioperative bleeding and ischemic complications.
Main Results:
- Overall complication rate was 11.6% (55/477 patients).
- Bleeding complications occurred in 32 patients, ischemic in 19.
- Bleeding complications were significantly more frequent after THA/TKA compared to other surgeries (p=0.003).
Conclusions:
- Patients with cardiac disease undergoing THA and TKA have a significantly higher incidence of bleeding complications.
- The risk of bleeding complications after THA/TKA is elevated compared to other musculoskeletal surgeries.
- Bleeding complications after these procedures may not be easily predictable.
Abstract:
Backround: The purpose of the study was to ascertain the incidence of bleeding and ischaemic complications in patients with cardiac disease after total hip arthroplasty (THA) and total knee arthroplasty (TKA).
Methods:
In total, 477 patients (289 women, 188 men) with known history of cardiac disease or thromboembolic disease treated with surgery in 2010-2013, were enrolled in the study. Perioperative prevention of thromboembolic disease using low-molecular-weight heparins was applied in all the patients. The data that could have an impact on the development of monitored perioperative complications, were observed.
Results:
Complications occurred in 55 (11.6 %) patients: bleeding complications in 32, ischaemic in 19, and both in four patients. Complications were found in 13 (12.0 %) patients after THA and in 6 (9.5 %) patients after TKA. Bleeding complications were observed in 17 patients after THA and TKA, ischaemic in one, and both simultaneously in one patient.Bleeding complications occurred insignificantly more frequently after THA and TKA (p = 0.094); however, this difference was statistically significant after adjustment for risk factors (p = 0.003). On the contrary, ischaemic complications were significantly more frequent after other skeletal surgeries (p = 0.014). Nevertheless, this difference was not statistically significant after the adjustment (p = 0.880). The comparison of the risk of complications in patients after THA with that in patients after TKA showed no significant difference (p = 0.580).
Conclusion:
The study showed a significantly higher incidence of bleeding complications in patients after THA and TKA compared to other surgeries of the musculoskeletal system in patients with a history of cardiac disease. Bleeding complications cannot be detected in advance (Tab. 1, Ref. 16).
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