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Related Experiment Video

Updated: Mar 8, 2026

The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders

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Published on: August 5, 2017

Overlapping memory trace indispensable for linking, but not recalling, individual memories.

Jun Yokose^1,2, Reiko Okubo-Suzuki^1,2, Masanori Nomoto^1,2

¹Department of Biochemistry, Faculty of Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

Science (New York, N.Y.)

|January 28, 2017

Summary

A small group of shared neurons in the amygdala links memories, enabling one memory cue to trigger another. Silencing these neurons disrupts memory association but not individual memory recall.

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Last Updated: Mar 8, 2026

The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders

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Published on: August 5, 2017

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Simultaneous Long-term Recordings at Two Neuronal Processing Stages in Behaving Honeybees

Simultaneous Long-term Recordings at Two Neuronal Processing Stages in Behaving Honeybees

Published on: July 21, 2014

Area of Science:

Neuroscience
Memory Research
Behavioral Science

Background:

Memories are integrated into networks, not isolated.
Mechanisms of memory association are not fully understood.

Purpose of the Study:

Investigate the neural basis of memory association.
Identify the neuronal ensembles mediating links between memories.

Main Methods:

Used conditioned taste aversion (CTA) and auditory-cued fear conditioning (AFC) in mice.
Examined neuronal ensemble overlap in the basolateral amygdala.
Silenced overlapping neuronal ensembles to assess memory retrieval.

Main Results:

CTA conditioned stimulus presentation triggered AFC conditioned response after memory coactivation.
Increased overlapping neuronal ensembles in the basolateral amygdala were observed.
Silencing overlapping ensembles suppressed CTA retrieval-induced freezing, without affecting individual memory recall.

Conclusions:

A small population of coshared neurons mediates the link between memories.
These shared neurons are crucial for memory association but not for recalling individual memories.