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Updated: Mar 8, 2026

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique
Published on: September 10, 2014
Sutureless extraocular muscle biopsy technique
Tom Kornhauser1, Ahed Imtirat1, Jaime Levy1
1Department of Ophthalmology, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva - Israel.
Purpose:
To describe a simple and novel technique of obtaining an extraocular muscle (EOM) biopsy.
Methods:
Our sutureless method involves obtaining a full-thickness 3-mm EOM specimen using a disposable punch biopsy.
Results:
The procedure was performed successfully, with no worsening of eye movement, muscle weakness, or cosmetic defects postoperatively. The acquired full-thickness specimen was sufficient for analysis.
Conclusions:
This technique to obtain an EOM biopsy allows a straightforward sutureless method, providing an adequate sample for tissue scrutiny.

