Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

6.0K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.0K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

663
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
663
Papillary Dermis01:11

Papillary Dermis

6.5K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
6.5K
Reticular Dermis01:15

Reticular Dermis

5.3K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
5.3K
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

9.9K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
9.9K
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

16.3K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
16.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PEGylated liposomes enhance the pharmacokinetics, biodistribution, anticancer efficacy, and safety of Kaempferol, a phytomolecule enrolled in clinical trials.

Scientific reports·2026
Same author

Bulk and surface engineered drug delivery system of repurposed drug enhances low-dose gemcitabine efficacy in pancreatic cancer.

International journal of pharmaceutics·2025
Same author

Optimizing medication therapy in elderly patients: The impact of medication review using STOPP and START criteria version 2.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners·2024
Same author

Pathophysiology-Driven Approaches for Overcoming Nanomedicine Resistance in Pancreatic Cancer.

Molecular pharmaceutics·2024
Same author

Health technology assessment for digital health Technologies in India: a framework for action.

International journal of technology assessment in health care·2024
Same author

Integrative management of insomnia during cancer chemotherapy: A case report.

Journal of Ayurveda and integrative medicine·2024
Same journal

Severe combined immunodeficiency (SCID) with pigmentary mosaicism: A coincidental occurrence in a child.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Agminated multifocal eruptive lobular capillary haemangiomas - An uncommon presentation.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Patch testing in India: Are we missing clinically relevant allergens?

Indian journal of dermatology, venereology and leprology·2026
Same journal

Double-loading technique for improved suspension retention on the recipient site in non-cultured epidermal cell suspension (NCES).

Indian journal of dermatology, venereology and leprology·2026
Same journal

Late-onset metastatic melanoma arising from a medium-sized congenital melanocytic naevus.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Custom-compounded glycine-proline jelly for ulcers in prolidase deficiency.

Indian journal of dermatology, venereology and leprology·2026
See all related articles

Related Experiment Video

Updated: Mar 8, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

784

Perilesional Leucoderma in Lichen Planus.

K Pavithran

    Indian Journal of Dermatology, Venereology and Leprology
    |January 28, 2017
    PubMed
    Summary
    This summary is machine-generated.

    A rare case shows leucoderma (white patches) developing around lichen planus, followed by the disappearance of the lichen planus. This suggests an autoimmune link between lichen planus and vitiligo.

    More Related Videos

    Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
    05:44

    Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

    Published on: June 10, 2025

    1.3K
    Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture
    10:31

    Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture

    Published on: April 8, 2016

    15.2K

    Related Experiment Videos

    Last Updated: Mar 8, 2026

    Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
    05:39

    Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

    Published on: May 16, 2025

    784
    Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
    05:44

    Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

    Published on: June 10, 2025

    1.3K
    Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture
    10:31

    Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture

    Published on: April 8, 2016

    15.2K

    Area of Science:

    • Dermatology
    • Immunology
    • Pathogenesis of skin conditions

    Background:

    • Lichen planus is an inflammatory condition affecting skin and mucous membranes.
    • Vitiligo is a condition characterized by depigmentation of the skin.
    • Autoimmune processes are implicated in various dermatological disorders.

    Observation:

    • A patient presented with a halo of leucoderma surrounding a plaque of lichen planus on the leg.
    • The perilesional leucoderma preceded the spontaneous regression of the central lichen planus lesion.

    Findings:

    • The development of leucoderma adjacent to lichen planus was observed.
    • Spontaneous resolution of the lichen planus plaque occurred after the onset of leucoderma.

    Implications:

    • This case suggests a potential shared autoimmune etiology between lichen planus and vitiligo.
    • Further research into autoimmune mechanisms may elucidate the relationship between these two dermatoses.
    • Understanding this association could lead to novel therapeutic strategies for both conditions.