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Ehlers- Danlos Syndrome.

Prasanta Basak, A J Kanwar, Surrinder Kaur

    Indian Journal of Dermatology, Venereology and Leprology
    |January 28, 2017
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    Summary
    This summary is machine-generated.

    Ehlers-Danlos syndrome type II, a connective tissue disorder, can cause skin hyperextensibility and fragile skin. Daily vitamin C supplementation showed potential benefits for managing symptoms.

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    Area of Science:

    • Medical Research
    • Dermatology
    • Genetics

    Background:

    • Ehlers-Danlos syndrome (EDS) is a group of inherited connective tissue disorders.
    • EDS Type II is characterized by specific clinical manifestations affecting skin and joints.
    • Understanding the pathophysiology and treatment options for EDS is crucial for patient management.

    Observation:

    • A female patient presented with a history of Ehlers-Danlos syndrome type II since infancy.
    • Clinical manifestations included significant skin hyperextensibility and characteristic cigarette paper scars at trauma sites.
    • These symptoms indicate compromised tissue integrity and wound healing.

    Findings:

    • The patient received a daily dosage of 1 gram of vitamin C.
    • Vitamin C supplementation appeared to be beneficial in managing the patient's EDS symptoms.
    • Further investigation is warranted to confirm the efficacy of vitamin C in EDS.

    Implications:

    • Vitamin C may play a role in improving connective tissue integrity in Ehlers-Danlos syndrome.
    • This finding suggests a potential adjunctive therapy for EDS patients.
    • Further clinical trials are needed to establish definitive treatment guidelines involving vitamin C for EDS.