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Research prioritization of men's health and urologic diseases

Tyler Okland1, Chante Karimkhani2, Hannah Pederson1

  • 1University of Colorado School of Medicine, Aurora, Colorado, USA.

International Braz J Urol : Official Journal of the Brazilian Society of Urology
|January 28, 2017
PubMed

Insights

Systematic reviews in the Cochrane Database of Systematic Reviews (CDSR) do not fully reflect disease burden for men's health and urologic diseases (MHUDs). Research prioritization needs to better consider global disease impact to reduce disparities.

Area of Science:

  • Urology
  • Public Health
  • Evidence-Based Medicine

Background:

  • The Cochrane Database of Systematic Reviews (CDSR) is a key resource for evidence-based medicine.
  • Systematic reviews guide clinical practice and health policy.
  • Understanding the alignment between research representation and disease burden is crucial for equitable resource allocation.

Purpose of the Study:

  • To assess whether the representation of men's health and urologic diseases (MHUDs) in the CDSR reflects their global disease burden.
  • To inform future research prioritization for MHUDs.

Main Methods:

  • Ten MHUDs were evaluated for their representation in the CDSR.
  • Disease burden was quantified using disability-adjusted life-years (DALYs) from the Global Burden of Disease (GBD) Study.
  • Spearman rank analysis was used to correlate CDSR representation with DALYs.

Main Results:

  • Nine out of ten MHUDs had at least one systematic review in the CDSR.
  • A weak, statistically insignificant positive correlation (rho = 0.42, p = 0.23) was found between CDSR representation and disease burden.
  • CDSR representation was misaligned with disease burden for the majority of conditions (6/10).

Conclusions:

  • Current representation of MHUDs in the CDSR does not adequately reflect disease burden.
  • Disease burden should be a stronger consideration in research prioritization processes.
  • Addressing research disparities globally requires awareness and strategic prioritization of research efforts.
Abstract

Keywords:
Infertility, MaleMen’s HealthUrologic Diseases

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