Sequence-Selective Binding of Oligopeptides in Water through Hydrophobic Coding

Joseph K Awino1, Roshan W Gunasekara1, Yan Zhao1

  • 1Department of Chemistry, Iowa State University , Ames, Iowa 50011-3111, United States.

Summary

Researchers developed nanoparticle receptors using "hydrophobically coded dimples" to achieve sequence-specific peptide binding. This breakthrough enables precise recognition of peptide features, advancing molecular recognition technologies.

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