Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Residuals and Least-Squares Property01:11

Residuals and Least-Squares Property

9.7K
The vertical distance between the actual value of y and the estimated value of y. In other words, it measures the vertical distance between the actual data point and the predicted point on the line
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
9.7K
Regression Toward the Mean01:52

Regression Toward the Mean

7.3K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
7.3K
Calibration Curves: Linear Least Squares01:20

Calibration Curves: Linear Least Squares

4.7K
A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
For data that follow a straight line, the standard method for fitting is the linear...
4.7K
Multiple Regression01:25

Multiple Regression

4.2K
Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
4.2K
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

1.3K
This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
1.3K
Quantifying and Rejecting Outliers: The Grubbs Test01:02

Quantifying and Rejecting Outliers: The Grubbs Test

4.3K
Sometimes, a data set can have a recorded numerical observation that greatly  deviates from the rest of the data. Assuming that the data is normally distributed, a statistical method called the Grubbs test can be used to determine whether the observation is truly an outlier.  To perform a two-tailed Grubbs test, first, calculate the absolute difference between the outlier and the mean. Then, calculate the ratio between this difference and the standard deviation of the sample. This...
4.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The stability of critical distance theory model for high cycle fatigue limit prediction of foreign object damaged blade samples.

Scientific reports·2026
Same author

Refer-ASV: Referring Multi-Object Tracking in Autonomous Surface Vehicle Navigation Scenes.

Journal of imaging·2026
Same author

Covalent Organic Framework with Tailored Angstrom-Scale Motifs for Efficient Water Activation and Desalination.

ACS applied materials & interfaces·2026
Same author

Forest therapy for psychological stress and emotional disorders: a systematic review and meta-analysis.

BMC public health·2026
Same author

Highly-dispersed ZrO<sub><i>x</i></sub> modulates C-O bond activation for boosting CO<sub>2</sub> hydrogenation to higher alcohols.

Chemical communications (Cambridge, England)·2025
Same author

Corrigendum to "Drug repositioning with metapath guidance and adaptive negative sampling enhancement" [J. Biomed. Inform. 171 (2025) 104916].

Journal of biomedical informatics·2025
Same journal

Hidden Data Recovery and Forecasting via Next-Generation Reservoir Computing With Multiscale Delay Selection.

IEEE transactions on neural networks and learning systems·2026
Same journal

CAFF-CIL: Causality-Aware Freedom Forgetting Approach for Class-Incremental Learning.

IEEE transactions on neural networks and learning systems·2026
Same journal

Harmonic Autoencoding Framework for Multiple Tasks in Magnetic Particle Imaging Reconstruction.

IEEE transactions on neural networks and learning systems·2026
Same journal

A Survey on Human-Centric Voice-Face Multimodal Learning.

IEEE transactions on neural networks and learning systems·2026
Same journal

Vision-Assisted Foundation Model for Solving Multitask Vehicle Routing Problems.

IEEE transactions on neural networks and learning systems·2026
Same journal

FP3O: Enabling Proximal Policy Optimization in Multiagent Cooperation With Parameter-Sharing Versatility.

IEEE transactions on neural networks and learning systems·2026
See all related articles

Related Experiment Video

Updated: Mar 8, 2026

Eye-tracking to Distinguish Comprehension-based and Oculomotor-based Regressive Eye Movements During Reading
05:54

Eye-tracking to Distinguish Comprehension-based and Oculomotor-based Regressive Eye Movements During Reading

Published on: October 18, 2018

6.8K

Groupwise Retargeted Least-Squares Regression.

Lingfeng Wang, Chunhong Pan

    IEEE Transactions on Neural Networks and Learning Systems
    |January 28, 2017
    PubMed
    Summary
    This summary is machine-generated.

    We introduce the groupwise retargeted least squares regression (GReLSR) model for multicategory classification. GReLSR improves classification by regularizing translation values within classes, outperforming existing methods.

    More Related Videos

    Author Spotlight: Impact of Intergenic Interactions on Disease-Identifying Dark Biomarkers
    03:37

    Author Spotlight: Impact of Intergenic Interactions on Disease-Identifying Dark Biomarkers

    Published on: March 1, 2024

    1.4K
    Utilizing vmTracking to Improve the Accuracy of Multi-Animal Pose Estimation in Rodent Social Behavior Studies
    07:34

    Utilizing vmTracking to Improve the Accuracy of Multi-Animal Pose Estimation in Rodent Social Behavior Studies

    Published on: November 7, 2025

    388

    Related Experiment Videos

    Last Updated: Mar 8, 2026

    Eye-tracking to Distinguish Comprehension-based and Oculomotor-based Regressive Eye Movements During Reading
    05:54

    Eye-tracking to Distinguish Comprehension-based and Oculomotor-based Regressive Eye Movements During Reading

    Published on: October 18, 2018

    6.8K
    Author Spotlight: Impact of Intergenic Interactions on Disease-Identifying Dark Biomarkers
    03:37

    Author Spotlight: Impact of Intergenic Interactions on Disease-Identifying Dark Biomarkers

    Published on: March 1, 2024

    1.4K
    Utilizing vmTracking to Improve the Accuracy of Multi-Animal Pose Estimation in Rodent Social Behavior Studies
    07:34

    Utilizing vmTracking to Improve the Accuracy of Multi-Animal Pose Estimation in Rodent Social Behavior Studies

    Published on: November 7, 2025

    388

    Area of Science:

    • Machine Learning
    • Computer Science
    • Pattern Recognition

    Background:

    • Multicategory classification is a fundamental task in machine learning.
    • Existing methods like Retargeted Least Squares Regression (ReLSR) have limitations in regularization.
    • There is a need for improved classification models with enhanced discriminative power.

    Purpose of the Study:

    • To propose a novel groupwise retargeted least squares regression (GReLSR) model.
    • To enhance multicategory classification by introducing class-specific regularization.
    • To improve upon the performance of existing ReLSR and discriminative least-squares regression methods.

    Main Methods:

    • Developed a new formulation of ReLSR explicitly expressing translation values.
    • Introduced a groupwise constraint to the ReLSR framework, creating the GReLSR model.
    • Incorporated additional regularization to restrict translation values within the same class.

    Main Results:

    • The proposed GReLSR model demonstrated superior performance on various machine learning datasets.
    • GReLSR effectively utilizes regularization to ensure similarity of translation values within classes.
    • Discriminative least-squares regression is shown to be a special case of ReLSR within the new formulation.

    Conclusions:

    • The GReLSR model offers a significant advancement in multicategory classification.
    • The groupwise constraint effectively enhances the discriminative capability of least-squares regression.
    • GReLSR represents a new state-of-the-art approach for multicategory classification tasks.