Association between cardiovascular diseases and mobility in persons with lower limb amputation: a systematic review

Sara Kaptein1, Jan H B Geertzen1, Pieter U Dijkstra1,2

  • 1a Department of Rehabilitation Medicine , Center for Rehabilitation, University Medical Center Groningen, University of Groningen , Groningen , The Netherlands.

Insights

Cardiovascular diseases in individuals with lower limb amputation are linked to poorer mobility and a reduced likelihood of becoming a prosthetic walker. Further research is crucial for optimizing rehabilitation strategies.

Area of Science:

  • Rehabilitation Medicine
  • Cardiology
  • Prosthetics

Background:

  • Lower limb amputation frequently co-occurs with cardiovascular diseases, potentially impacting recovery.
  • Reduced cardiac function in these patients can complicate post-amputation rehabilitation.

Purpose of the Study:

  • To systematically review the association between cardiovascular diseases and mobility outcomes in individuals with lower limb amputation.

Main Methods:

  • A comprehensive search of four databases was conducted for studies published before August 2016.
  • Studies were identified using keywords related to amputation, cardiovascular diseases, and mobility.
  • Inclusion criteria were applied to titles, abstracts, and full-text articles.

Main Results:

  • Ten studies met the inclusion criteria.
  • Cardiovascular diseases were associated with cardiac complications during rehabilitation.
  • Seven studies indicated that cardiovascular diseases decrease the likelihood of prosthetic walking and negatively affect mobility outcomes.

Conclusions:

  • Evidence on the impact of cardiovascular diseases on mobility post-amputation is varied.
  • Cardiovascular diseases are linked to reduced prosthetic walking success and poorer mobility.
  • High-quality research is needed to inform pre- and post-amputation rehabilitation for individuals with cardiovascular disease.
Abstract

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