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Updated: Mar 8, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
[Primary infection with cytomegalovirus: An infectious cause of splenic infarction]
H Kassem1, K Khamadi1, C Farrugia2
1Service de médecine interne, centre hospitalier Sud-Essonne, site Dourdan, 2, rue du Potelet, 91410 Dourdan, France.
Introduction:
Cytomegalovirus-associated thrombosis has been extensively reported in the medical literature, mainly in immune-compromised patients. However, the association with splenic infarcts has rarely been reported.
Case Report:
We report a 32-year-old Caucasian and immunocompetent woman who presented with a splenic infarction during a primary infection with CMV. The differential diagnostic ruled out embolic, hematologic, gastrointestinal and coagulation disorders. The outcome was favorable with symptomatic treatment.
Conclusion:
A primary infection with CMV must be added to the diagnostic work-up in the presence of a febrile splenic infarction, especially when it is associated with a biological mononucleosis reaction.
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