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Prevention and Therapy of Pediatric Emergence Delirium: A National Survey
Christopher Huett1, Torsten Baehner1, Felix Erdfelder1
1Department of Anesthesiology and Intensive Care, Bonn University Hospital, Sigmund Freud Str. 25, 53105, Bonn, Germany.
Insights
Propofol is the preferred choice for preventing and treating pediatric emergence delirium (ED) among German anesthesiologists. Current practices show underrepresentation of alternative therapies and midazolam-centered premedication strategies.
Area of Science:
- Anesthesiology
- Pediatric Medicine
- Pharmacology
Background:
- Pediatric emergence delirium (ED) is a common yet controversial issue regarding its pharmacological prevention and treatment.
- Existing evidence on various treatment options for ED is often limited and inconclusive.
Purpose of the Study:
- To investigate current clinical practices in the prevention and treatment of pediatric ED.
- To understand the routine management strategies employed by anesthesiologists in Germany.
Main Methods:
- A web-based survey was distributed to members of the German Society of Anesthesiology.
- The survey collected data on ED management, facility structure, and patient demographics.
Main Results:
- 88% of respondents consider ED a significant clinical problem, but only 5% use formal assessment scores.
- Oral midazolam is the standard premedication for 84% of respondents.
- Total intravenous propofol anesthesia is the primary prevention strategy (63%).
- Experienced anesthesiologists favor propofol for ED treatment, while less experienced ones prefer opioids.
- Propofol received the highest satisfaction ratings for ED treatment.
Conclusions:
- Propofol is the leading choice for pharmacological prevention and treatment of ED in German pediatric anesthesia.
- Alternative therapeutic options and non-midazolam premedication strategies are currently underutilized.
Introduction:
Although pediatric emergence delirium (ED) is common, preventive and therapeutic pharmacological treatment is the matter of an international controversial discussion and evidence on different options is partially vague.
Objective:
We therefore examined clinical routine in prevention strategies and postoperative therapy of ED with respect to clinical experience in pediatric anesthesia.
Methods:
A web-based survey was developed investigating routine management (prevention and treatment) of ED, facility structure, and patient population. The link was sent to all enlisted members of the German Society of Anesthesiology.
Results:
We analyzed 1229 questionnaires. Overall, 88% reported ED as a relevant clinical problem; however, only 5% applied assessment scores to define ED. Oral midazolam was reported as standard premedication by 84% of respondents, the second largest group was 'no premedication' (5%). The first choice prevention strategy was to perform total intravenous (propofol) anesthesia (63%). The first choice therapeutic pharmacological treatment depended on clinical experience. Therapeutic propofol was preferentially chosen by more experienced anesthesiologists (5 to >20 patients per week, n = 538), while lesser experienced colleagues (<5 patients per week, n = 676) preferentially applied opioids. Dexmedetomidine (1%) and non-pharmacological (2%) therapy were rarely stated. The highest satisfaction levels for pharmacological therapy of ED were attributed to propofol.
Conclusions:
Propofol is the preferred choice for pharmacological prevention and treatment of ED among German anesthesiologists. Further therapy options as well as alternatives to a midazolam-centered premedication procedure are underrepresented.
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