Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

8.6K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.6K
Anatomy of the Intestines01:23

Anatomy of the Intestines

89.0K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
89.0K
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

1.3K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.3K
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.4K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.4K
Development of Immunocompetence01:22

Development of Immunocompetence

1.1K
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
1.1K
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

15.2K
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
15.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a robotic training curriculum for visceral and gastrointestinal surgical trainees: an international Delphi study.

The British journal of surgery·2026
Same author

Association of skill and errors with outcomes in robotic rectal cancer surgery.

Surgical endoscopy·2025
Same author

Fellowship of the European Board of Surgery in the specialty of Minimally Invasive Surgery (F.E.B.S./MIS): a continuous evaluation.

Surgical endoscopy·2025
Same author

Diagnostic accuracy of the faecal immunochemical test and volatile organic compound analysis in detecting colorectal polyps: meta-analysis.

BJS open·2025
Same author

Frailty and body composition predict adverse outcomes after emergency general surgery admission: a multicentre observational cohort study.

Annals of the Royal College of Surgeons of England·2024
Same author

Deep learning prediction of error and skill in robotic prostatectomy suturing.

Surgical endoscopy·2024
Same journal

Effect of Endoscopic Retrograde Appendicitis Therapy on Postoperative Gastrointestinal Function in Patients With Chronic Fecalith Appendicitis.

Gastroenterology research and practice·2026
Same journal

Divergent Trajectories of the Burden of MASLD Attributable to High Fasting Plasma Glucose in China and Globally: A GBD Study 1990-2021 and Projections to 2046.

Gastroenterology research and practice·2026
Same journal

From "Monarch, Minister, Assistant, and Envoy" to "Microbial Dialogue": A Review of Novel Mechanisms by Which Chinese Herb Pairs Improve Metabolic Diseases Through Gut Microbiota Metabolic Regulation.

Gastroenterology research and practice·2026
Same journal

Effects of Aging on Correlation of Striated Esophageal and Pharyngeal Deglutitive Motor Function.

Gastroenterology research and practice·2026
Same journal

RETRACTION: "Influence of Rosiglitazone on the Expression of PPAR<i>γ</i>, NF-<i>κ</i>B,and TNF-<i>α</i> in Rat Model of Ulcerative Colitis".

Gastroenterology research and practice·2026
Same journal

High Prevalence of Sarcopenia in Noncirrhotic Women With Primary Biliary Cholangitis: A Comparative Study of Clinical Characteristics and Risk Factors.

Gastroenterology research and practice·2026
See all related articles

Related Experiment Video

Updated: Mar 8, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

975

Is Month of Birth a Risk Factor for Colorectal Cancer?

N K Francis1, N J Curtis2, E Noble3

  • 1Department of General Surgery, Yeovil District Hospital NHS Foundation Trust, Higher Kingston, Yeovil BA21 4AT, UK; Faculty of Science, University of Bath, Wessex House 3.22, Bath BA2 7AY, UK.

Gastroenterology Research and Practice
|January 31, 2017
PubMed
Summary
This summary is machine-generated.

Colorectal cancer risk appears higher for individuals born in autumn, particularly September. Conversely, those born in spring show a reduced risk, suggesting a potential seasonal birth effect on cancer development.

More Related Videos

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

7.5K
Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
07:13

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

837

Related Experiment Videos

Last Updated: Mar 8, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

975
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

7.5K
Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
07:13

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

837

Area of Science:

  • Epidemiology
  • Oncology
  • Public Health

Background:

  • The developmental origins of health and disease (DOHaD) hypothesis suggests early-life factors influence later health.
  • Season of birth has been associated with various chronic conditions, including cancers.
  • The specific relationship between birth season and colorectal cancer risk remains unexplored.

Purpose of the Study:

  • To investigate the potential association between month and season of birth and the risk of colorectal cancer.
  • To determine if seasonal birth patterns are evident in individuals diagnosed with colorectal cancer.

Main Methods:

  • A case-control study design was employed.
  • Month of birth data were collected from a colorectal cancer patient database.
  • Age- and gender-matched controls were used for comparison.
  • Generalized linear models with Poisson and negative binomial responses were utilized to analyze seasonal patterns.

Main Results:

  • The study included 1019 colorectal cancer patients and 1277 controls.
  • A statistically significant seasonal effect was observed, with an excess of colorectal cancer cases among those born in autumn (p = 0.026).
  • Individuals born in spring showed a reduced risk compared to autumn births. A September birth peak indicated a 14.8% higher risk than the spring trough.

Conclusions:

  • A discernible seasonal influence exists on the birth timing of individuals undergoing colorectal cancer surgery.
  • There is a disproportionate excess of colorectal cancer diagnoses among individuals born in September.
  • Further large-scale studies are warranted to confirm these seasonal birth effect findings in colorectal cancer.