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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Corneal Topographic and Aberrometric Measurements Obtained with a Multidiagnostic Device in Healthy Eyes:
David P Piñero1, Alberto López-Navarro2, Inmaculada Cabezos1
1Group of Optics and Visual Perception, Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain.
Abstract:
Purpose. To evaluate the intrasession repeatability of corneal curvature, eccentricity, and aberrometric measurements obtained with a multidiagnostic device in healthy eyes. Methods. This study enrolled 107 eyes of 107 patients ranging in age from 23 to 65 years. All of them underwent a complete anterior segment examination with the VX120 system (Visionix-Luneau Technologies, Chartres, France). Three consecutive measurements were obtained. The within-subject standard deviation (S ), intrasubject precision (1.96 × S ), and intraclass correlation coefficient (ICC) were calculated. Results. All S for corneal power measurements were below 0.26 D, with ICC above 0.982. The S for corneal astigmatism at different areas (3, 5, and 7 mm) was below 0.21 D, with ICC above 0.913. Concerning the axis of astigmatism, its S was below 11.27°, with ICC above 0.975. The S and ICC for corneal eccentricity were 0.067 and 0.957, respectively. The S and ICC for high-order aberration root mean square (RMS) were 0.048 µm and 0.901, respectively. For 3rd- and 4th-order aberrometric parameters, all S were below 0.037 µm and all ICC were higher than 0.84, except for quadrafoil RMS (ICC: 0.689). Conclusions. The multidiagnostic device evaluated is able to provide consistent measurements of corneal power, eccentricity, and third- and fourth-order aberrations in healthy eyes.

