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Multiple Keratocanthomas on the Mons Pubis and Labia Majora
Abstract:
An ederly woman developed multiple keratoacanthomas on the mons pubic and labia majora. Some lesion coalesced to from large irregular plaques with multiple craters. Biopsy of a well developed nodule revealed keratin - filled craters, pseudoepitheliomatous hyperplasia with horn pearls and dyskeratosis of prickle cells which appeared eosinophilio and glassy. Though a few lesions involuted spontaneously, some persisted. These responded well to topical 5-fluorouracil therapy. There was no recurrence of lesions, on long follow-up.
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